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Implementation Resources

Calculators and Tools

Detroit Medical Center Calculator

The Detroit Medical Center (DMC) Calculator is based on first-order pharmacokinetic equations (Cp1=Cp0∗e−kt) and uses patient’s demographics and clinical information to help empirically dose patients. It carries some standard population-based pharmacokinetic parameters such as Vd estimations of 0.65 L/kg for normal hospitalized patients, using variable weight, there are varied ke equations from the Ducharme (aggressive) ke equation of ke=CrCl*0.0016, to the Matzke equation (least aggressive for significant comorbidity patients) ke=(0.00083*CrCl) + 0.0044. Specific colorings exist (red = less preferred) to help nudge clinicians to pick preferred empiric population kinetics. It utilizes a two-level calculator for AUC to calculate patient-specific pharmacokinetics.

Detroit Medical Center Calculator
NEW! Contagion Article: Vancomycin AUC Implementation in Resource-Limited Settings and its Associated Difficulties

The latest article from SIDP illustrates the challenges of area under the curve (AUC) implementation and offers insights for strategies and resources to overcome them.
Link to Article

Calculators and Tools

The 1-2-3’s of Vanc AUC: Tips for AUC-Based Dosing Implementation

A ready-to-use slide set for educating clinicians on implementing vancomycin AUC-based dosing.

Vancomycin AUC Slides


The 1-2-3’s of Vanc AUC

A downloadable, printable all-in-one infographic to assist you in educating clinicians on implementing vancomycin AUC-based dosing.



The information provided by the MAD-ID Vancomycin Task Force (“we,” “us” or “our”) on this website (the “Site”) is for general informational purposes only. All information on the Site is provided in good faith, however we make no formal endorsement(s) of any kind regarding use of any proprietary materials found within this content. Under no circumstance shall we have any liability to you for any loss or damage of any kind incurred as a result of the use of the site or reliance on any information provided on the site. Your use of the site and your reliance on any information on the site is solely at your own risk.

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